VitalVibe collagen peptides could reduce muscle soreness after intense exercise, as shown in a scientific, randomized, and controlled study [5]. Twenty-four healthy, recreationally active males took a daily dose of 2×10 g of VitalVibe or a placebo, along with a Vitamin C-rich drink from 7 days before to 2 days after performing 150 drop jumps. Forty-eight hours after exercise, participants were asked to rate their muscle soreness on a visual analog scale from 0 (no pain) to 200 mm (unbearable pain).
Figure 2. Total number of awakenings during the night, measured after 7 days of supplementation (A) objectively by polysomnography on the 7th night or B) subjectively by a validated questionnaire the morning of day 8. * Indicates a significant difference between the two groups, p < 0.05.
An additional indication of an improved night’s sleep was that participants in this study improved their scores in the baseline Stroop Color and Word test, a validated cognitive test measuring response time and accuracy to test if they could process two stimuli at the same time.
Participants are presented with a word (black letters on a white background) describing a color and asked to select the corresponding color by pressing the corresponding key (Figure 3A). The morning after the sleep trial, participants consuming VitalVibe scored higher on the test, indicating they improved their response accuracy as a result of better sleep.
Figure 3. (A) Visualization of the baseline Stroop cognitive test. (B) Response accuracy, measured as the number of correct responses (arbitrary units) in the baseline Stroop test on the morning after the sleep trial. In the VitalVibe group, there was no variability in their scores.
Fueling victory: gut comfortin athletic performance
Strenuous exercise can cause gastrointestinal discomfort because it affects the intestinal barrier function. The tight junctions between intestinal cells that are meant to protect us, can open up due to intense training. This can result in elevated blood endotoxin levels, which causes inflammation, leading to digestive issues and affecting sports performance (Figure 4).
Schematic representation of a healthy vs. an inflamed intestinal barrier
Figure 4. (A) Healthy intestinal barrier, (B) disturbed intestinal barrier. Strenuous exercise can perturb tight junctions between intestinal cells and increase intestinal permeability to microorganisms and toxins, potentially leading to digestive issues.
Rousselot showed that supplementation with 10 g of VitalVibecollagen peptides 7 days prior to, and 45 min before a 70 min run, could lessen the increase of blood endotoxin levels, a known cause of inflammation, two hours after exercising [9].
Figure 5 shows the results of this randomized, placebo-controlled, crossover study performed in 20 healthy, recreationally active athletes. When taking VitalVibe, no difference in blood endotoxin levels was observed before or after exercise, contrary to the significantly elevated levels when drinking flavored water. This suggests that collagen peptides might support intestinal barrier function, thereby reducing the presence of endotoxins in the blood.
As mentioned above, very intense sports performance is often associated with gastrointestinal symptoms. Although it is known that this discomfort can be intensified by some sports supplements used to promote performance, our study shows that symptoms reported in the VitalVibe group were comparable to the control (flavored water) [9]. These findings indicate that the impact of VitalVibe on the gut during strenuous exercise is comparable to that of flavored water.
Figure 5. Blood endotoxin levels measured with no exercise or two hours post-exercise, having ingested VitalVibe or placebo. Blood endotoxin levels were not significantly different between the non-exercise group and the VitalVibegroup 2 hours after exercise. * Indicates a significant difference between the two groups, p ≤ 0.05.
Collagen and whey: friends with benefits
Protein supplement usage among athletes, both professional and recreational, is a well-established practice, with whey protein being by far the most popular choice. While a consumption of 45 g of whey protein is currently recognized as the gold standard, blending diverse protein sources might enable targeting different components of the musculoskeletal system. Since collagen peptides are known for their beneficial effects on mobility and recovery after exercise, why not merge the established advantages of collagen peptides with whey?
In a double-blind, randomized, parallel-group study, the impact of daily consumption of 20 g of VitalVibe and 25 g of whey was compared to the prevailing standard of 45 g/day of whey. In twenty-two healthy, active men, performance was evaluated by measuring the jump height of counter movement jumps before and after a 3-week training program combined with supplementation of either whey (W) or whey with VitalVibe collagen peptides (WP).
More than just another protein
Looking after our bones is key to enjoying an active life, whether you are 25 or 75. Bones are living tissues that are constantly renewed in a carefully balanced process of synthesis and breakdown.
VitalVibe stimulates bone formation cells more than casein. A study performed in mouse bone cells shows that the potential of VitalVibe to improve bone health (the balance between cell formation and breakdown) is the result of its collagen peptide composition rather than mere proteins [11].
These in vitro experiments demonstrate that the digested and absorbed collagen peptides stimulate the formation of cells responsible for bone synthesis (Figure 8A) more than casein (milk protein), while simultaneously inhibiting the formation of cells that break down bones (Figure 8B).
Figure 8. Influence of digested VitalVibe on the growth of bone metabolism cells in vitro. (A) Growth of bone formation cells or osteoblasts, (B) growth of bone breakdown cells or osteoclasts.
Sporty and mobile lifestyle for all
Over time, the balance between synthesis and breakdown of cartilage gets disturbed. This can lead to joint pain, stiffness, and reduced mobility.
In a scientific, randomized, placebo-controlled study [10], elderly women with mild joint discomfort reported a significant reduction in painful symptoms, such as stiffness and pain, after oral intake of VitalVibe (8 g/day) (Figure 6). These positive effects also improved their mobility and joint function within three months (Figure 7).
Figure 6. Symptom-relieving effects of VitalVibe: development of the WOMAC score assessing joint function discomfort (decreased score = improvement) after the intake of VitalVibe or placebo over a duration of 6 months (Jiang, 2014).
Figure 7. VitalVibe improves joint functionality: development of the Lysholm score assessing joint function (increased score = improvement) after the intake of VitalVibe or placebo over a duration of 6 months (Jiang, 2014).