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Beauty from Within
THE SCIENCE BEHIND SKIN & HAIR BEAUTY BROUGHT TO YOU by VITALVIBE COLLAGEN PEPTIDES
There has always been a link between beauty and health: beautiful skin quickly tells those around us that we’re in good health—and, in fact, looking good can make us feel better physically and mentally. Healthy-looking skin, in short, is associated with attractiveness and confidence. This holistic well-being is one of VitalVibe’s key pillars: we are here to help consumers look their best.
What the science tells us
Rousselot’s scientific research has shown that collagen peptides can delay the signs of aging and improve the appearance of skin and hair. More than 10 years of Rousselot studies demonstrate that oral intake of VitalVibe collagen peptides can help us achieve firmer skin and healthier-looking hair.
Collagen and beauty
Collagen, the body’s most abundant protein, is crucial for our skin. It’s responsible for its strength and flexibility (Box 1: Skin structure). Collagen also supports hair and nails, the skin’s main appendages, even though they are not made of collagen.
Around our mid-twenties, collagen production in our skin diminishes, leading to well-known signs of aging: wrinkles, dry skin, and loss of elasticity [1]. Hair also becomes thinner and weaker, which can eventually lead to hair loss [2].
The future of beauty
Our scientific portfolio is constantly growing with new findings, as we use the latest technologies to better understand collagen’s role in promoting beauty from within.
Discover the latest insights into VitalVibe and beauty from within! (Box 2: VitalVibe Science for Skin and Hair Beauty)
Box 1: Skin structure
VitalVibe and the science behind skin beauty.
Skin density
Our placebo-controlled studies have shown that VitalVibe can increase skin firmness by improving skin density.
The Asserin et al. scientific study on 99 Caucasian women (age 40-65) [3] demonstrated that ingestion of 10 g of VitalVibe F for 12 weeks significantly increased skin density compared to placebo (Figure 1a).
Similar positive results were observed in the Vleminckx et al. study with 85 Chinese women (age 40-65) [4], where a significant improvement in skin density was observed after taking 5 g of VitalVibe P for 12 weeks (Figure 1b), compared to the placebo group.
Figure 1. Effect of 12 weeks of VitalVibe supplementation on skin density. (A) 10 g VitalVibe F in Caucasian women using high frequency, real-time ultrasound; (B) 5 g VitalVibe P in East Asian women, measured by ultrasound scanning and subsequently quantified on a gray-scale (0-255). * p < 0,05; ** p < 0,01 compared to placebo
Skin elasticity
Skin elasticity is vital for a healthy appearance, as the loss of elasticity leads to sagging and wrinkling of the skin [3]. In our studies, VitalVibe positively impacted skin elasticity.
In the Vleminckx et al. study [4], a dermatology expert assessed skin elasticity with clinical scoring (0-9) based on visual and tactile assessment (Figure 2a). The results demonstrate that after four weeks of oral supplementation with 5 g of VitalVibe P, the participants’ skin elasticity significantly improved by 7% compared to placebo.
This beneficial effect on skin elasticity was confirmed in the Kuninty et al. study of 40 Caucasian women (age 35-48) using gold-standard elasticity-measuring technology after 12 weeks of supplementation with different VitalVibe F dosages [5]. Positive effects were already observed with 2.5 g of VitalVibe within 12 weeks. Oral intake of 5 to 10 g of VitalVibe F significantly elevated skin elasticity compared to placebo within 12 weeks (Figure 2b).
Figure 2. : (A) Clinical scoring of skin elasticity after four weeks of oral supplementation of 5 g VitalVibe P in East Asian women. (B) Changes in skin elasticity (mean and 95% CI) in Caucasian women under 48 years old, compared to placebo (pink line at Δ = 0) after 12 and 24 weeks of oral supplementation with VitalVibe F at different dosages. * p < 0.05, ** p < 0.01 compared to placebo at a given time point.
Skin hydration
For a natural glow, our skin needs sufficient hydration. VitalVibe has been observed to improve skin hydration levels.
The study conducted by Asserin et al. [3] showed that a daily dose of 10 g VitalVibe P significantly improved skin hydration in 33 healthy Japanese women within 8 weeks compared to a placebo (Figure 3a). Additionally, supplementation with either VitalVibe P or VitalVibe F significantly enhanced skin hydration levels after 8 weeks when compared to baseline.
The Vleminckx et al. study on 85 Chinese women (age 40-65) shows that daily supplementation with only half the dose (5 g) of VitalVibe P was sufficient to increase skin hydration (Figure 3b; [4]). This study demonstrates a significant difference between the VitalVibe and placebo group after 12 weeks. Notably, the participants also used a face cream during the study period to standardize their facial care, highlighting the efficacy of VitalVibe in combination with routine skincare.
Facial care, combined with VitalVibe supplementation, enhances the results, making them valuable as they mimic real-life beauty routines.
The positive effects of VitalVibe supplementation on skin hydration were further confirmed in the Kuninty et al. study [5]. This study showed that after 24 weeks, beneficial effects could be observed even with lower dosages (2.5-5 g) (Figure 3c), while in the placebo group, skin hydration decreased over time. Taking 10 g of VitalVibe F significantly improved skin hydration already within 12 weeks compared to the placebo.
Figure 3. : Assessment of skin hydration (A) by conductivity in a Japanese population after supplementation with VitalVibe P or VitalVibe F; (B) clinical scoring by a dermatology expert in 40-65-year-old East Asian women after supplementation with VitalVibe P. (C) Changes in skin hydration (mean and 95% CI) in women under 48 years old, compared to placebo (pink line at Δ = 0) with VitalVibe F at different dosages. * p < 0.05; ** p < 0.01 denotes significant differences between VitalVibe and placebo group at a given time point.
Wrinkle reduction
We call them ‘laugh lines’, but many of us do not welcome those wrinkles around the eyes or mouth, which are one of the most common physical signs of aging. Our research has revealed that VitalVibe can reduce wrinkle visibility in women .
In the placebo group, this significant effect was only observed after 12 weeks, possibly due to the properties of the face cream. This study shows that VitalVibe
works faster against wrinkles than using a face cream alone.
Finally, considering that VitalVibe can help improve skin hydration, density, and elasticity, it is concluded that overall wrinkle appearance can be diminished by VitalVibe supplementation.
Figure 4. : Influence of VitalVibe on the appearance of wrinkles: a) depth of crow’s feet wrinkles in East Asian women after supplementation with VitalVibe P. $$ p < 0.05 compared to baseline (Week 0).
Dosage & origin: which is the best choice?
Together, the studies mentioned above illustrate that VitalVibe can positively impact skin beauty and wrinkle visibility. Beneficial effects were obtained after supplementation with different dosages [5], but it’s worth noting that the desired results might be achieved more quickly with a higher daily dose. The demonstrated effects were observed independently of the VitalVibe raw material used and across populations with diverse ethnicities.
VitalVibe and the science behind hair beauty
We all know how our hair can influence our mood. A good hair day means looking and feeling good. However, many people may not realize that diminishing hair health doesn’t just come with aging. Stress, hormones, and even seasonal shifts can affect our hair and, consequently, lead to hair loss. Hair care is essential for everyone.
Zooming in on hair
First, we need to take a closer look at our hair (Figure 5). Aside from the visible part on your scalp, hair also contains a second structure called the hair follicle, located inside the skin. This hair follicle is a living mini-organ, containing hair follicle stem cells (HFSCs) responsible for the growth and structure of our hair. The presence of these HFSCs ensures that our hair keeps growing and renewing through the regulation of the hair cycle. Disturbances in the growth cycle of these hair cells can result in (age-induced) hair loss. To maintain our hair, we need to keep our stem cells healthy and active.
Figure 5. Schematic representation of a hair follicle.
Growing beautiful hair from within
As hair follicles are situated in the skin, nurturing healthy hair starts from within. One promising solution is VitalVibe. The pioneering ex vivo Pappelbaum et al. study on hair follicles, harvested from six people (men and women, age 27-59), revealed that in vitro digested VitalVibe B (mimicking the body’s digestive process) increases the amount
of active stem cells (HFSCs) in the hair follicle (Figure 6a) and inhibits their death (Figure 6b) [7]. Since the aging process is linked to a decline of HFSCs, these findings suggest that VitalVibe may play a positive role in addressing (age-induced) hair loss by reinforcing the stem cells and, consequently, sustaining hair follicle health.
Figure 6. : Effect of VitalVibe B on A) presence and B) death of hair follicle stem cells: Hair follicles were harvested from six human donors and cultured ex vivo in the presence or absence of 0.01 mg/ml in vitro digested VitalVibe or blank. * p < 0.05.
As hair does not contain collagen, this pioneering study demonstrates that VitalVibe’s benefits may extend beyond the effects of collagen production. It’s a clear indication that collagen peptides could support the HFSCs and keep them active and alive. This, in turn, could contribute to effective hair care and beauty.
